Easy ISI is a series of mini courses with basic concepts about biotechnology that can both encourage students to become interested in the area and update professionals already working.
There will be four classes, in the morning and afternoon, in the Auditorium of the Vinicius Fonseca Administrative Center (Av. Brasil, 4365 – Vinicius Fonseca Administrative Center – Manguinhos) and online.
See the topics below with their respective instructors and guarantee your place on the courses of interest:
In person in the auditorium of the Vinicius Fonseca Administrative Center
Organizers:
Isabella Maluf, Fernando Serva and Felipe Rodrigues
Presentation:
In this course on digital transformation in the pharmaceutical industry, teachers will present solid knowledge about the opportunities and challenges brought about by the digital transformation processes underway in the main biopharmaceutical industries around the world. With presentations of successful cases in various sectors of the biopharmaceutical industry (related to digital transformation), we will discuss benefits and opportunities brought about by the introduction of technologies and tools in the digital transformation processes occurring in the biopharmaceutical industry. The discussion will also address the use of technologies/tools such as artificial intelligence, robotics, digital twins, augmented/virtual realities, among others in the sector. Opportunities for using digital technologies/tools will be presented in different areas of the biopharmaceutical industry, from technological development, through production and quality areas to management activities.
Program content:
– Concepts, technologies and digital tools proposed for a digital transformation process in the biopharmaceutical industry
– Benefits/Advantages of digital transformation in the biopharmaceutical industry
– Barriers/Challenges for implementing digital technologies in the biopharmaceutical field
– Application cases of digital technologies/tools in the biopharmaceutical industry and in Bio-Manguinhos
Teachers:
Elcio Brito
Fabricio Costa, Delloite
Bruno Jorge, ABDI
Mediation:
Fernando Serva and Felipe Rodrigues
Online with access by the link https://bit.ly/3xmo8pP
Coordinators:
Christiane Marques and Wagner José Tenório dos Santos
Presentation:
Update and informative analysis on the characteristics of Digital Health and the importance of New Information Technologies and artificial intelligence in disease prevention and health promotion for the Public Health System. The course aims to provide participants with an overview of the potential of using artificial intelligence applied to diagnosis, including new tools, applications, medical devices, among others, with a focus on the applicability of solutions in the SUS.
Program content:
– Artificial intelligence for health data processing: machine learning and internet of things.
– Diagnostic technology and digital health – Digital transformation in health.
– Intersection of medicine and technology – The Digital Health specialist on the list of careers of the moment.
– Public health through wireless technologies in the prevention, monitoring and diagnosis of diseases.
Teachers:
Jerônimo Ruiz, Fiocruz Minas (Machine learning and Internet of Things (IoT) applied to diagnosis)
João Bosco de Oliveira Filho, Brazilian Society of Clinical Pathology / Laboratory Medicine – SBPC/ML (Advances in diagnosis using Omic Sciences)
Carlos Eduardo Gouvea, Brazilian Chamber of Laboratory Diagnostics – CBDL (Diagnostic technology and digital health – digital transformation in health)
Mediation:
Wagner Tenório
In person in the auditorium of the Vinicius Fonseca Administrative Center
Coordinators:
Aline Oliveira, Carla Gottgtroy, Adriana Danowski, Amanda Marques, Marisol Simões, Martín Bonamino
Presentation:
The increasing availability of advanced therapy products (APT) in Brazil highlights the urgent need to understand the technological bases of these products, as well as their particularities in the manufacturing processes and the regulatory frameworks that govern these therapies. With this in mind, this mini-course aims to offer a comprehensive overview of PTAs, from their conception to clinical application, while discussing the challenges faced in making them available to the population. Throughout the course, we will cover essential definitions of PTAs and the regulatory path they take from conception to clinical application, as well as explore the global landscape of PTAs, including costs, trends, and development pipelines. Cases of class I and class II PTAs such as MSC cell therapy, AAV gene therapy, and CAR-T cell/gene therapy will also be presented. Additionally, a panel discussion on the “Challenge of Incorporating Advanced Therapies into the Healthcare System” will conclude the course, providing an opportunity to explore critical issues and possible solutions related to the adoption and implementation of advanced therapies in the public health context. This course is essential for professionals in the health, medical-scientific, regulatory and academic areas interested in updating themselves on this emerging and promising field of medicine.
Program content:
– Definitions of PTAs and regulatory path – from conception to clinical application
– Global PTA Scenario (costs / trends / development pipelines)
– Cases of PTAs class I, class II (MSC cell therapy? TIL?, AAV gene therapy, CAR-T cell/gene therapy)
– Challenges of effective incorporation into the SUS – aspects linked to technology, natural history of the disease and organizational aspects
Teachers:
Renata Parca, Anvisa
Aline Oliveira, Fiocruz/Bio-Manguinhos
Martín Bonamino, Inca and Fiocruz
Discussants:
Thaís Catão, Carla Gottgtroy and Denizar Vianna.
Online with access via the link https://bit.ly/3xmo8pP
Organizers:
Luciane Gaspar, Perla Vilani, Ana Carolina Cajaraville
Presentation:
Adjuvants play a crucial role in the effectiveness of vaccines. Traditional adjuvants, such as aluminum salts, have been used effectively in several vaccines over the last 80-90 years, as widely documented in the scientific literature. However, the evolving landscape of vaccines being developed for more complex pathogens also requires the exploration of new and innovative adjuvant solutions. The search for new adjuvants to induce a stronger and/or different types of immune response is, therefore, increasingly critical in the design of vaccines. Furthermore, increased demand for crucial components also demands improved and sustainable supply chains for critical components.
The course on Adjuvants will be structured into three distinct blocks to provide a comprehensive understanding of the topic. In the first block, participants will be introduced to the concept of adjuvants and their general applications in vaccine formulation. We will explore the characteristics, mechanisms of action and selection criteria of the different classes of adjuvants to enhance the immunological response to the antigen. The second block will be dedicated to presenting new technologies and products available on the market, highlighting the next generation of adjuvants with an emphasis on sustainable production. Finally, in the third block, a practical example of the use of adjuvants in the development and production of vaccines will be presented, providing participants with a clear understanding of how these substances are applied in practice. This course was designed for professionals interested in improving their knowledge about adjuvants and their application in vaccine formulation.
Program content:
Ana Carolina (Fiocruz/Bio-Manguinhos/LATEV)
-General introduction – Contextualization, History and trends in the development of adjuvants.
Dennis Christensen (Croda)
– Characteristics, mechanism of action, selection criteria of different classes of adjuvants for human use (viral, bacterial and therapeutic vaccines for cancer)
– Adjuvant systems under development and licensed available on the global market
– New generation of adjuvant systems with sustainable manufacturing chain (squalene, saponin, others)
– How to define the best adjuvant for different types of antigens: proteins, VLPs, viruses, mRNA, DNA) – as a decision trio
– Formulations: how to balance the complexity of the adjuvant system and the complexity of the antigen to obtain an ideal formulation.
Paulo Lee Ho (Butantan Institute)
– Case Study: Development of the IB160 adjuvant for use in a pandemic situation
Teachers:
Ana Carolina Cajaraville
Dennis Christensen (Croda)
Paulo Lee Ho, Butantan
Mediation:
Ana Carolina Cajaraville and Luciane Gaspar
Easy ISI courses are aimed at students and professionals who would like to update themselves on course topics.
The instructors are professionals with great technical/scientific capacity and recognized prominence in their areas of knowledge.
The courses will be in person and online and it is not necessary to be registered at the 8th ISI to participate.
Easy ISI courses are open to all 7th ISI participants, whether they are students or professionals in the field who would like to update themselves on the course subjects.
Course instructors are professionals of high technical/scientific ability and recognized standing in their fields.
Easy ISI courses will not have simultaneous translation. All Easy ISI courses are taught in Portuguese. Participants must be proficient in the language of the chosen course.
5 courses will be given in-person during the event, with registration open only to participants of the in-person modality, and 1 will be given online and open to all symposium registrants.
Os cursos do Easy ISI são voltados para estudantes e profissionais que gostariam de se atualizar sobre os assuntos dos cursos.
Os instrutores são profissionais de grande capacidade técnica/científica e de reconhecido destaque nas suas áreas de conhecimento.
Os cursos Easy ISI são inclusivos e terão tradução simultânea em português / inglês / libras.
Os cursos serão presenciais e online e é necessário estar inscrito no 8th ISI para poder participar.
