The Event

The main objectives of the sixth edition of the International Symposium on Immunobiologicals (ISI) were the promotion of innovation, the generation of cutting-edge knowledge, and networking among specialists to accelerate the development of biotechnology solutions for public health problems. In the 2021 edition, the ISI gained a digital format, which allowed remote participation in the lectures, round tables, mini-courses and workshops, which were broadcast in real time from the virtual platform specially designed to respond to this new reality imposed by the pandemic. In 2022 ISI became a hybrid event, which also included face-to-face sessions following all security protocols, once the pandemic stage made it possible to return to some physical contact. Whether in person or through the virtual platform, ISI is the ideal place to seek cutting-edge knowledge in the field of biotechnology worldwide, meet leading researchers and scientists, share what you are doing and hear feedback from your peers in the poster area, as well as get updates on important topics for careers in the field and find out what prominent companies in the market are offering.

The full schedule is available for access on the app. Register and access now!

Check out what happened at the 6th ISI

Want to know a summary of how the International Symposium on Immunobiologicals (ISI) went or to see a bit of the daily program?


Games as a tool for innovation

On May 5th at 9am, the 6th ISI invited its participants to experience a playful and at the same time collaborative and instigating moment through an online escape game session.

Innovation does not always mean the creation of something new, but rather the capacity we have to give new uses and meanings, to improve, evolve, and even propose new forms to something that already exists, and this is where games fit in.

Fun, team interaction and information exchange without the need for technical-scientific knowledge are just a part of what this experience provided.

Learn more about the initiative.

Access now


Poster Exhibition

Those registered for the 6th ISI can click here to visit the poster exhibition of this edition.

You will be directed to the application, where you will have full access to the exhibition with posters, videos of the authors and download the proceedings of the event. In addition to seeing this year’s papers, you can interact with the authors to ask questions, make comments, and even seek ideas and partnerships for your own research.

You can also visit the Bio Lounge and our sponsors.

If you are not registered yet, click here and register now!

We will have a post-event program that you can still attend.


Open for Post-Event Programming

The 6th ISI is over, but you can still access the full program through our application. And even better, if you haven’t registered, you can still do so and have access to the event and also to the post-event Webinar that will be announced soon!

Registration is open to all professionals or students, and researchers in the field of immunobiologicals and related areas, from institutions involved in the production and/or technological development of vaccines, biopharmaceuticals, or diagnostic reagents, as well as those involved in public health. They are also aimed at entrepreneurs, startups, investors and development agencies. Registration is free for both Brazilians and foreigners, as long as they meet the above requirements.


6th ISI 2022 Schedule

Check the schedule for the 2022 event

  • May 3rd

  • Sem título

  • Thrombin – Technological development of a national biological sealant
    Fabricio Klerynton Marchini, ICC – Fiocruz / PR*

  • Coral da Fiocruz
    – Socorro Gross, PAHO* – Arnaldo Correia de Medeiros, SVS/MoH – Sandra de Castro Barros, SCTIE/MoH – Marco Krieger, Fiocruz* – Mauricio Zuma, Bio-Manguinhos* – Akira Homma, Bio-Manguinhos*

  • VAC-01. Second-generation Vaccines: Adjuvants and Booster Doses
    Gabrielle Gimenes Lima, USP

  • – Ann Ottosen, UNICEF* – Kate O’Brian, WHO* – Andres de Francisco, PAHO* – Akira Homma, Bio-Manguinhos*
    Chair: Mauricio Zuma, Bio-Manguinhos*

  • VAC-03. Recombinant influenza virus encoding a Streptococcus pneumoniae conserved antigen: a bivalent intranasal and intramuscular broad-spectrum vaccine against pneumonia and Flu
    Kimberly Freitas Cardoso, Fiocruz/Instituto René Rachou

  • – South Africa – Caryn Fenner, Afrigen Biologics and Vaccines* – Argentina – German Sanches, Sinergium* – Brazil – Patricia Neves, Bio-Manguinhos*
    Chair: Rami Sharf, PATH*

  • ORT-01. Median Tissue Culture Infectious Dose (TCID50) as a validated tool to measure antiviral activity in functionalized textiles
    Adriana de Souza Azevedo Soares, Bio-Manguinhos

  • – Imelda Jordaan, Afrigen Biologics and Vaccines* – Analía Acebal, Sinergium – Gustavo Mendes, Anvisa
    Chair: Jelena Berglund, PATH


  • May 4th

  • Sem título

  • Idea to Injection: Flexible and modular platforms to optimize your manufacturing
    Katarina Stenklo, Cytiva

  • – Strategies for collaboration and management of complex projects through the procurement of technology services, Thomas Gerlach, Pannex Therapeutics* – Plant-based production platform as a strategy for acceleration of the development of biologics, Don Stewart, Plantform Canada
    Chair: Hugo Defendi, Bio-Manguinhos*

  • BIO-01. Development and optimization of a protocol for 19BBz CAR-T cells generation
    Leonardo Ribeiro Batista Silva, INCA

  • Talk – innovation hub: Innovative researchers and their innovative startups.
    – Aruã Prudenciatti, CROP – UNESP – Carolina Caliari, In Situ – USP-Ribeirão Preto – Myrian Pruschinski , Skinzymes – USP*
    Chair: Eduardo Emrich, Biominas*
    Azul claro
    Sem título

  • BIO-02. Evaluation of antitumor activity of 5 rna interference in conjunction for the treatment of breast cancer in nude mice
    Ana Beatriz Teixeira Frederico, Bio-Manguinhos

  • – Flexibility and agility in defining and operating a new production site, Eduardo Estrada, Sanofi* – New technologies and strategies in biopharmaceutical manufacturing, Andreas Castan, Cytiva*
    Chair: Luiz Alberto Lima, Bio-Manguinhos*

  • MAN-01. The challenges of VTC-WWTP management in meeting legal requirements in times of COVID-19 pandemic
    Vinícius Mattos de Mello, Bio-Manguinhos

  • – Vaccination of premature babies at CRIE in Brazil – what have we learned? Ana Paula Burian, CRIE / Vitória – ES* – Real-world evidence of hexavalent vaccination introduced in Chile: rational and results, Juan Pablo Torres Torreti, Universidad de Chile*
    Chair: José Cassio de Moraes, Santa Casa de São Paulo*

  • May 5th

  • Azul claro
    Sem título

  • The revolutionary potential of mRNA as a platform for biopharma
    Birgit Rogell, Roche CustomBiotech EMEA/LATAM

  • – Self-testing experience as a strategy to expand the HIV diagnostic, Mariana Villares, DST-AIDS* – Regulatory framework for new IVD technologies, Marcella Abreu, Anvisa
    Chair: Rosane Cuber, Bio-Manguinhos*

  • IVD-02. New approaches for recombinant protein VP1-2A of HAV production and characterization based on liquid microarray assay: application for developing a point-of care diagnostic test
    Michel Vergne Felix Sucupira, Bio-Manguinhos

  • – The use of large-scale, rapid whole-genome sequencing of SARS-CoV-2 to understand viral transmission and evolution, Lorenzo Subissi, OMS* – Pandemic of SARS- CoV- 2 in Brazil: evolution and emergence of variants of concern, Marilda Siqueira, Fiocruz*
    Chair: Marco Krieger, Fiocruz*

  • IVD-01. Development and Validation of Reverse Transcription Loop- Mediated Isothermal Amplification (RT-LAMP) for Rapid Detection of SARS-CoV-2 in Human Samples
    Bárbara Nazly Rodrigues Santos, Fiocruz

  • – Rebecca Farkas, CEPI* – David Kaslow, PATH* – Peter Dull, B&MGF
    Chair: Sotiris Missailidis, Bio-Manguinhos*

  • – Daniel Pacheco Lacerda, Unisinos* – Maria Cristina de Cunto Brandileone, Adolfo Lutz Institute* – Maria Notomi Sato, USP* – Marco Antonio Stephano, USP* – Paulo Lee Ho, Butantan Institute* – Mauricio Zuma, Bio-Manguinhos*
    Event close-up remarks
    Akira Homma, Bio-Manguinhos

    Cinza escuro

Easy ISI

During the morning of May 3 and 4, the 6th International Symposium on Immunobiologicals offered the Easy ISI, a series of six mini-courses, taught on the event’s virtual platform. The main objective was to introduce some basic concepts of biotechnology in order to stimulate students’ interest in the area, as well as to update professionals already working in the field.

The classes had limited vacancies, but are already available for watching. Learn more about the courses and watch the classes.

Access now


ISI Webinar Series

Regaining High Vaccination Coverage

On the morning of April 7th, the first webinar of the 6th ISI was presented, open to all registrants and inaugurating this year’s symposium application. The theme of this first webinar was “Regaining High Vaccination Coverage” and featured experts in the field, who discussed the risks identified with the recent drops in vaccination coverage, pointing out the problems, how they impact the indicators and the search for possible solutions to reverse this scenario.

Read more



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